safeT21

婦健 Femina Healthcare 4D Ultrasound, Prenatal Diagnosis & Treatment Centre 8 704-707 ( A2 ) Suite 704-707, Grand Centre, 8, Humphrey Avenue, Tsim Sha Tsui (TST MTR A2 Exit) 23682333

Non-invasive Prenatal Screening or Testing (NIPS or NIPT)

Booking telephone: 23682333

Special Discount price from December 2018 till February 2019:

1. safeT21 from $4600 (discount price, original price $6000)

2. safeT21 Advance Panel $6500 (original price $8000)

3. safeT21 + Fragile X screening from $5900 (original $7000)

4. safeT21 + Fragile X screening $7500 (Original $10000)

5. NIFTY $3500 (original price $5000)

6. NIFTY-PRO: 95 items, 84 microdeletion & microduplication $3800 (Original price $7000)

7. Harmony $4000 (performed in USA original price $5500)

8. Panoram Basic/Extended Panel $4500/$5500 (Original price $6000/$8000)

9. Vistara 30 single gene mutations $15,000 (original price $20,000)

(affecting cardiac, skeletal and neurology)

https://www.feminahealthcentre.com/vistara-natera

https://www.natera.com/vistara/conditions

safeT21 Express (Standard $4600 or Advanced $6500)

$4600 Standard Panel, 14 well-validated chromosomal conditions covered

$6500 Advanced Panel safeT21 checked 46 chromosomes, 3 billions base pairs

PANORAMA (performed in USA, $4500; + microdeletion $5500)

HARMONY (performed in USA & well validated, special $3700)

PACKAGE:

Those with NIPT done at our clinic will pay $500 less for the Anomaly Scan

Except for those who had standard panel safeT21

 

NIPT is originally developed for the screening of Down syndrome.

1. Test performs at or after 9-10 weeks pregnant.

2. Most common trisomies (13, 18 & 21) can be screened

Down Syndrome, Edward & Patau syndromes.

3. Most sex chromosome abnormalities

Turner syndrome, Jacob, Klinefelter syndromes.

4. Triploidy can be detected by Panorama test.

5. Microdeletion chromosomal abnormalities:

DiGeorge syndrome (22q11.2, prevalence 1 in 1000);

1p36 deletion (Prevalence 1 in 5000);

Cri-du-chat syndrome (Prevalence 1 in 20000);

Angelman syndrome (Prevalence 1 in 12000)

Prader Willi syndrome (Prevalence 1 in 10000).

NIFTY-PRO test offers 85 microdeletion and duplication.

Most conditions will cause mental retardation.

6. safeT21 Advanced Panel:

Checked all 3 billions base pairs

Also screens many microdeletion or chromosomal abnormalities.

It offers most comprehensive and thorough screening.

It can detect 3 millions base pairs defect, millions of possible abnormalities.

Standard Panel safeT21 covered 14 chromosomal conditions.

7. Vistara NIPT Single Gene Mutation Screening

https://www.feminahealthcentre.com/vistara-natera

Achondroplasia, Osteogenesis Imperfecta, Thanatophoric Dysplasia 1 & 2

Hypochondroplasia & Ehlers Danlos syndrome.

Tuberous sclerosis 1 & 2, Epileptic Encephalopathy

Intellectual disability (SYNGAP1).

Noonan syndrome, Sotos syndrome, Apert syndrome, Rett syndrome

Muenke syndrome, CHARGE syndrome, LEOPARD syndrome

Pfeiffer syndrome, Jackson Weiss syndrome,

Juvenile myelomonocytic leukemia.

During pregnancy, the unborn child releases DNA into mother's blood.

NIPT measures the amount of DNA from chromosomes 21, 18 and 13 in the blood.

An abnormally increased amount of chromosome 21 DNA is suggestive of Down syndrome.

Large-scale clinical studies have shown:

1. NIPT can detect >99% of Down syndrome fetuses.

The test has a false-positive rate of 0.1%.

2. NIPT can detect 95-99% of Trisomy 18 (Edward syndrome) fetuses.

It has a false-positive rate of 0.4%.

3. NIPT can detect 90-95% of Trisomy 13 (Patau syndrome).

All abnormal result need invasive prenatal procedure to confirm (amniocentesis).

Other chromosome abnormality can be detected:

A. Sex chromosome aneuploidies)

B. Other syndromes (e.g. microdeletions related syndromes)